ADEME/DGA 2022 – Novel molecular approaches for chromo-fluorogenic detection of cyanide ions.


Funding (ICMUB): 120 000 €

Duration: oct. 2022 – 38 months

Scientific leader ICMUB: Anthony ROMIEU


Summary

Environmental pollution by cyanides and organic cyanide compounds is still a very current issue. Indeed, their use in several sectors of industry is indispensable but these activities (even if they are theoretically carried out within a well-defined regulatory framework) combined with deviant behavior (e.g., voluntary discharges, chemical terrorism) pose heavy threats to humans, groundwater and ecosystems. Therefore, the detection and measurement of these toxic pollutants are regularly carried out to verify that their levels are below those set by national legislation and/or international standards. Access to efficient, easy-to-use and inexpensive environmental analysis equipment is therefore essential. This is the context of this research project, which aims to develop an innovative fluorescence detection system for cyanide ions, which should enable two distinct objectives to be achieved.

Objective 1 (ADEME): to obtain a selective fluorescent chemical dosimeter for cyanide ions, to carry out environmental analyses on polluted site (water, soil samples) in a simple, easy-to-use format that can be implemented with a compact and portable fluorometer.

Objective 2 (AID/DGA): carry out the selective detection of tabun, an organophosphorus neurotoxicant bearing a cyanide as reactive leaving group.

Total funding: 504 600 €

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